Skin rejuvenation encompasses the use of varied technologies to smooth, tighten, even, or otherwise restore epidermal and dermal appearance. Given the prevalence of epidermal and dermal abnormalities in the population, demand for effective and safe skin rejuvenation procedures is high. Fortunately, significant advances in the arena of laser technology have provided effective and diverse options for skin rejuvenation.

Excess or unwanted hair is a common problem affecting both genders. With the introduced theory of selective photothermolysis and the development of laser technology, the field of hair epilation has vastly expanded in recent 40 years. Laser currently in use for hair removal includes the normal-mode ruby, normal-mode alexandrite, diode and Nd:YAG lasers. Laser hair removal has revolutionized the field of hair target and destroy hair follicles, leading to more long-lasting hair removal, requiring less operator dependency, and decreasing the potential risks.

Transdermal delivery offers advantages such as non-invasiveness and the ability to overcome first-pass hepatic metabolism. Human skin serves a protective function by imposing physicochemical limitations to the type of permeant that can traverse the barrier. In recent years, various passive and active strategies have emerged to optimize transdermal delivery. The passive approach entails the optimization of formulation or drug carrying vehicle to increase skin permeability. It has been demonstrated that passive methods do not greatly improve the permeation of drugs with molecular.